Coleus is a plant that has been used since ancient times in Ayurvedic and Hindu traditional medicine. The root portion has been traditionally used to treat colic, congestive heart failure, convulsions, eczema, hypertension, insomnia, painful urination and respiratory disorders.

also provides therapeutic benefit in angina, asthma, psoriasis and prevention of cancer metastases.

Nutrients & Benefits

Cosmetics: Forskolin when in high pure form 95%, increases isoform selectivity via acting on adenylyl cyclase to enhance the intracellular levels of cyclic adenosine monophosphate (AMP). The mechanism of increasing and maintaining lean body mass is link to the availability of cyclic AMP. By facilitating hormonal action, cyclic AMP may control the thermogenic response of the body to food, increase the utilization of body fat and enhance the metabolic rate of the body.

Skin problems: Coleus oil is useful in topical preparations, due to its antimicrobial properties. Coleus oil is particularly effective against propionibacterium acnes, the microorganism responsible for acne, and it has been found active against other microorganism known to be responsible for skin infections and eruptions.

Antioxidant: Forskolin shows high amount of polyphenols and higher antioxidant activity. Leaf extract of this plant exhibited significantly high amount of total polyphenols, flavonols and flavones and high antioxidant activity. Coleus can be used as an important source of phenolic compounds with significantly high antioxidant activity (Rasineni et al., 2008).

Weight Loss: As we mentioned, forskolin does have promising results in its ability to prevent weight gain in already overweight or obese people. Used in conjunction with a healthy lifestyle, it can be used to help manage a healthy weight.

This "power" herb has an active ingredient in it called forskolin. It has been used in ayruvedic medicine for many years. Forskolin's basic mechanism of action is that it increases the amount of cyclic AMP (adenosine monophosphate) in cells by activating an enzyme called adenylate cyclase. Cyclic AMP (cAMP) is one of the most important secondary messengers in the cell. It is considered to be one of the most important cell regulating compounds.

Under normal circumstances, cAMP forms by adenylate cyclase activation due to hormonal stimulation at the cell receptor site. However, forskolin seems to bypass this reaction and allows for an increase in intracellular cAMP to occur.

Why is it important to increase cAMP levels?

Well, there are several benefits of this to athletes including relaxation of the arteries and smooth muscles, lowering blood pressure, enhanced insulin secretion (which can help drive carbohydrates and protein into muscle cells for energy and recovery), increased thyroid hormone function (which can help enhance metabolic rate), and significantly increase lipolysis (fat burning). Forskolin also seems to benefit other cellular enzymes as well.

The breakdown of fat for fuel (lipolysis) is actually regulated by cAMP. Forskolin has been shown to not only enhance lipolysis but it may also inhibit fat storage from occurring. This is very good news for individuals trying to lose body fat and get lean.

Another way that forskolin may allow for fat loss to occur is by stimulating thyroid hormone production and release. Thyroid hormone controls metabolism and can enhance metabolic rate, which may translate into more fat loss.

May Be a Useful Alzheimer’s Treatment

Like a lot of research on forskolin, the research linking it with a treatment for Alzheimer’s is in its infancy. However, a promising study published in the Journal of Neuropathology and Experimental Neurology performed on rats in July 2016 found administration of forskolin greatly decreased many negative physical components caused by Alzheimer’s disease, including plaque in various areas of the brain and reduced inflammatory activity. This is incredibly encouraging in the area of natural Alzheimer’s treatment.

Lowers Blood Sugar Levels

A 2014 study on glycemia and oxidative stress in rats looked at forskolin’s effectiveness on the two conditions. The study, published in the International Journal of Medical Sciences, indicated that regular administration of forskolin (over the course of eight weeks) decreased fasting blood glucose levels. While this preliminary study shows that this supplement may help diabetic and prediabetic patients, more research must be done in order to prove its level of efficacy.

Miscellaneous uses

Coleus also works well in treating asthma, cancer, cardiopathy, congestive heart failure, convulsions, cramp, depression, dermatosis, dyspepsia, dysuria, eczema, glaucoma, high blood pressure, hypothyroidism, infertility, insomnia, ischemia, myocardosis, obesity, psoriasis, respirosis, thrombosis and water retention (Duke et al., 2002).

Varion® offers 4 premium Coleus Products:

Coleus Extract 10, 20, 40% is a mostly soluble, yellow red powder that is Kosher and food grade certified and is produced in a BRC certified facility.

Coleus Extract – 95% (Cosmetics Application) is a mostly soluble, fine creamish powder that is certified Kosher and food-grade certified and is produced in a BRC certified facility.

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